Pat McLamore led the Lil' Irish with 12 points.
It was the second time in four days Cansius had beaten a top Section Five class AA team. The Griffins beat Schroeder 71-55 at the East High RAP Invitational on Saturday.
The game was even at the half, but Canisius took a five point lead after the third quarter. A 10-4 run to open the fourth pushed that advantage to 11 with four minutes to play. Aquinas never got closer than seven the rest of the way.
Canisius improves to 15-2. Aquinas is now 11-3.
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